2019 GA meeting May 8 in Madrid

2018 GA MEETING

The 2018 GA meeting which took place on Thursday 3 May 2018 in Brugge, Belgium saw an increase in attendance from 2017. Hosted by Prince-Erachem, the meeting which lasted 5 hours saw several deliberations related to the last REACH deadline and its consequences thereafter including the possible re-structuring of the consortium.  Some key decisions taken by way of vote are as follows:

Some highlights:

  • Future structure of Mara: A more streamline structure to be established if the organisation is to continue functioning infinitely or in the event of a complete closure its mandate and members to be incorporated within the Mn trade association –The IMnI. Discussions are still on-going  
  • Collaboration: A clearly defined pathway for collaboration between Mara and the IMnI was established
  • Data-sharing Regulation: Approval of the reimbursement structure (to be executed in phases) in accordance with regulation 2016/9
  • Approval of the 2018 workplan and budget

Study Summaries

Compliance with any regulation, including REACH, requires that studies be conducted in order to fill data gaps. The Mn Consortium conducted studies on 14 different inorganic manganese-based substances. All of the studies complied with recognised guidelines as laid down by the relevant international organisations (including the OECD) and to good laboratory practice (GLP). For those countries that signed the OECD Mutual Acceptance of Data (MAD) agreement, the data listed below can be used for regulatory compliance as well as for in-house safety assessments.

Prenatal Developmental Toxicity Study in the Han Wistar Rat/Mn3O4/OECD 414/Oral/GLP
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Two Generation Reproduction Inhalation Toxicity Study/MnCl2/OECD 416/Rats/GLP
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Developmental Neurotoxicity Study in the Han Wistar Rat/MnCl2/OECD 426/Inhalation/GLP
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13-Week Inhalation Toxicity Study in the Wistar Rat /Mn metal/OECD 413/GLP/
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Prenatal Developmental Toxicity Study in the Han Wistar Rat/MnCl2/OECD 414/Inhalation/GLP
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ACUTE TOXICITY TO DAPHNIA MAGNA/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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ACUTE EYE IRRITATION IN THE RABBIT/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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ACUTE DERMAL IRRITATION IN THE RABBIT/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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IN VITRO SKIN CORROSION/ Sinter ore (Manganese ores, reduced)/ GLP
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ACUTE ORAL TOXICITY IN THE RAT/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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ASSESSMENT OF OCULAR IRRITATION POTENTIAL/ Sinter ore (Manganese ores, reduced)/ GLP
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DETERMINATION OF RELATIVE DENSITY/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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DETERMINATION OF FLAMMABILITY (SOLIDS)/ Sinter ore (Manganese ores, reduced)/ OECD 440/2008/ GLP
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DETERMINATION OF SKIN IRRITATION POTENTIAL/ Sinter ore (Manganese ores, reduced)/ GLP
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DETERMINATION OF WATER SOLUBILITY/ SiMn slag (Silicomanganese slag)/ OECD 440/2008/ GLP
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ACUTE EYE IRRITATION IN THE RABBIT/ SiMn slag (Silicomanganese slag)/ OECD 440/2008/ GLP
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ACUTE DERMAL IRRITATION IN THE RABBIT/ SiMn slag (Silicomanganese slag)/ OECD 440/2008/ GLP
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DETERMINATION OF GENERAL PHYSICO-CHEMICAL PROPERTIES/ SiMn slag (Silicomanganese slag)/ GLP
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IN VITRO SKIN CORROSION/ SiMn slag (Silicomanganese slag)/ GLP
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LOCAL LYMPH NODE ASSAY IN THE MOUSE/ SiMn slag (Silicomanganese slag)/ OECD 440/2008/ GLP
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